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  1. Advantages of delayed ventriculoperitoneal shunting in post haemorrhagic hydrocephalus seen in low birth weight infants
    Taylor, Allan Grant, 2018-01-09T08:55:19Z, University of Cape Town
    INTRODUCTION: The incidence of intraventricular hemorrhage (IVH) in very low birth weight infants is between 25 and 50%. Approximately 13-60% of these patients will develop progressive post hemorrhagic hydrocephalus (PHH) and of these 22- 70% will require CSF diversion. The most common therapeutic i ...
  2. The impact of costs and perceived quality on utilisation of primary health care in Tanzania : rural-urban comparison
    Munga, Michael A, 2018-01-09T08:54:51Z, University of Cape Town
    Health services utilisation, which is sometimes used as a proxy measure for equity is a complex subject to study. Identifying and explaining the important factors determining health care utilisation is a key to a better assessment of whether countries" health policies address the equity concerns of ...
  3. Gender differences in presentation and early survival in an antiretroviral therapy programme in Gugulethu : South Africa, 2002-2007
    Cornell, Morna, 2018-01-09T08:58:27Z, University of Cape Town
    By 2005, an estimated 500 000 people with HIV had initiated highly active antiretroviral therapy (HAART) in sub-Saharan Africa. However, disproportionately more women than men have accessed HAART in most developing countries including South Africa. While there has been considerable recent interest i ...
  4. An analysis of the utilisation of research information, in policy making and guidelines for the use of magnesium sulphate in the treatment of eclampsia and pre-eclampsia in South Africa
    Daniels, Karen Lorraine, 2018-01-09T08:58:34Z, University of Cape Town
    Background: The literature suggests that although the idea of using evidence to inform policy making has come into favour, actualising this idea in practice is complex. Within the framework of these debates this dissertation focuses on the uptake of findings from research into policy making for the ...
  5. Human macrophage model for selective evaluation of CD8⁺ and γδ⁺ cytotoxic T cell function in tuberculosis
    Passmore, Jo-Ann Shelley, 2018-01-09T14:13:55Z, University of Cape Town
    The human macrophage cell line U937 was investigated as an in vitro model for human macrophage function in mycobacterial infections. This involved evaluating the ability of differentiated U937 cells to phagocytose Mycobacterium tuberculosis, control intracellular mycobacterial growth, and present my ...
  6. The detection of occult metastatic disease in patients with cutaneous melanoma
    Hanekom Gideon S, 2018-01-09T14:13:27Z, University of Cape Town
    The ability to identify melanoma patients with progressive disease is central to efficient management. The challenge therefore, is to develop prognostic markers and techniques which will allow the identification of those patients whom, at the time of primary tumor diagnosis, already have micrometast ...
  7. The diversity of malignant rhabdoid tumours : a morphological, immunohistochemical and ultrastructural review of cases from the Red Cross Children"s Hospital and Groote Schuur Hospitals
    Mostert, Colin, 2018-01-09T14:13:07Z, University of Cape Town
    Malignant rhabdoid tumours of the kidney are rare childhood neoplasms. Extra-renal rhabdoid tumours are known to have a distinctive biological behaviour and do not always occur in the paediatric age group. As the histogenesis of rhabdoid tumours, and their apparent relationship to nephroblastoma is ...
  8. Regulation of melanogenesis in conditionally immortalised mouse melanocytes expressing a temperature-sensitive SV40 large T antigen
    Prince, Sharon, 2018-01-09T14:12:41Z, University of Cape Town
    The transformation of a normal melanocyte to a malignant melanoma involves a series of poorly understood genotypic and phenotypic alterations. In vitro models of melanoma formation generated by transforming mouse melanocytes with exogenous oncogenes have revealed that this process is frequently acco ...
  9. Birds of a white feather : a congenital hypopigmentary disorder in the chick
    Koubovec, Dominique Johanna, 2018-01-09T14:12:37Z, University of Cape Town
    Dominant white, a mutation of the I gene, leads to amelanosis and is common to many commercial breeds of fowl, including Pile Games, White Plymouth Rocks and White Leghorns. Despite much investigation on the cellular mechanisms of Dominant white, its mode of action is still poorly understood. The ai ...
  10. Assessment of and improvements to a stereophotogrammetric patient positioning system for proton therapy
    Hough, Jan K, 2018-01-09T14:11:43Z, University of Cape Town
    Summary in English. ...