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Showing results 41 to 50 of 162344

  1. An audit of endocrine dysfunction in children with craniopharyngiomas at Red Cross Children"s Hospital and Groote Schuur Hospital from 1976 to 2004
    Omarjee, Zakiyya, 2018-01-09T08:57:59Z, University of Cape Town
    Background: Craniopharyngiomas account for 6-10% of childhood brain tumours and are the third most common intracranial tumours of childhood. Despite their benign histological appearance, they are often associated with a poor outcome and have significant associated morbidity. Aim: To analyse the data ...
  2. An evaluation of the nutritional status of preschool chldren living in a rural health district : implications for a community based nutrition programme in the Northern Province
    Saitowitz, Romy, 2018-01-09T08:58:03Z, University of Cape Town
    The study aimed to evaluate the nutritional status of pre-school children (0-6 years), and the activities of a local CBNP serving these children, in the Ngwaritsi health district of the Northern Province. The following objectives were identified: o To determine the anthropometric status of children ...
  3. Epidemiology and prevention of rugby injuries amongst schoolboy, senior club and provincial rugby players in the Western Cape
    Upton, Patrick Anthony Howard, 2018-01-09T08:53:48Z, University of Cape Town
    This thesis comprises a series of independent investigations examining rugby injuries occurring to players from under 14 to senior provincial level in the Cape Province (now the Western Cape). The first two studies report data aimed at gaining a more detailed understanding of rugby injuries in speci ...
  4. The development, implementation and validation of a plasma-based high performance liquid chromatographic assay for Isoniazid and N-Acetylisoniazid: an acetylator status population study at Brewelskloof Hospital
    Cockcroft, Jennifer Jean, 2018-01-09T08:57:42Z, University of Cape Town
    A novel high performance liquid chromatographic assay has been developed for the simultaneous determination of isoniazid and N-acetylisoniazid in plasma. Solid phase extraction involving C18 columns is used to extract the drug and the metabolite from 0.5 ml plasma. The analyte peaks are resolved usi ...
  5. A cost analysis of the treatment of first-line uncomplicated malaria in the Tonga district of Mpumalanga
    Wilkins, Justin, 2018-01-09T08:57:37Z, University of Cape Town
    Following the completion of a detailed baseline study of malaria in the region, a model was developed to assess the cost-effectiveness of switching from chloroquine to sulfadoxine-pyrimetharnine as first line treatment in the Tonga district of Mpumalanga, South Africa, where malaria is seasonal and ...
  6. Cell type-specific regulation of the chicken tyrosinase promoter
    Clarke, Ruth Elsie, 2018-01-09T08:57:11Z, University of Cape Town
    Melanin, the pigment found in the eyes and coats of vertebrates, is synthesised by two main cell types: melanocytes and retinal pigment epithelial (RPE) cells. These two cell populations. which arise from distinct embryological origins, differ with respect to the rate at which they produce melanin a ...
  7. The role of the chicken gonadotropin-releasing hormone receptor C-terminal tail in expression and coupling
    Lopes, John, 2018-01-09T08:56:14Z, University of Cape Town
    The role of the carboxy terminal tail of the chicken gonadotropin-releasing hormone receptor was determined by testing the activity of a series of chicken gonadotropinreleasing hormone receptors with progressive deletions in their carboxyl terminus. The 55 amino acid carboxy terminal tail of the chi ...
  8. The effect of upper respiratory tract illness on exercise performance
    Viljoen, Deon Andre, 2018-01-09T08:53:44Z, University of Cape Town
    Two studies were undertaken to investigate the relationship between upper respiratory tract infection (URTI) and exercise performance. The first study documented the incidence of URTI in an athletic population and the second study determined the effect of URTI on exercise performance during the reco ...
  9. The protective role of tumour necrosis factor alpha in the heart
    Meiring, James Justus, 2018-01-09T08:54:08Z, University of Cape Town
    The pleiotropic cytokine tumour necrosis factor alpha (TNF╬▒) is produced by the heart in response to the ischaemic preconditioning (PC) stimulus. We hypothesised that this endogenously produced peptide may play a role in activating the ischaemic PC mediated tolerance towards a subsequent ischaemic i ...
  10. Risk factors and the effectiveness of back belts in the prevention of back pain amongst forklift drivers subject to whole body vibration exposure
    Joubert, Darren Mark, 2018-01-09T08:55:43Z, University of Cape Town
    Motivation: Back pain is a major cause of absenteeism, lost work time and increased compensation and medical costs amongst workers and has been estimated to cost $20 billion annually in the United States. Back pain has long been associated with the driving of forklifts, and is a complex area of occu ...